For example, if I want to test a ARM platform I use qemu because it is a processor emulator. I use VirtualBox for ISOs because that works for me.
Angus Hedger
I use VirtualBox for windows XP, Varied linux distros, BSD’s etc, on a Debian Squeeze x64 host (have also used it on a Windows Vista 64 and a Windows 7 64 host)
This is not the place for an answer. :)